According to the Bronsted-Lowry Acid-Base Model, an acid is any substance that contributes protons (Hydrogen ions) in solution. Equally, a base accepts protons from solution. Polyprotic substances can both contribute and donate protons and thus can act as buffers in the maintenance of pH. Another type of buffer system relies on the use of both a weak acid (an acid with a Keq value that isn't ridiculously high) and its Bronsted Lowry base conjugate (just the acid with one hydrogen removed and contributed to solution. If there are more than one hydrogen ion, then the substance is called polyprotic.

More simply, Arhhenius described an acid as any substance that releases hydrogen ions into solution and a base as any substance that releases hydroxide ions. Since hydroxide ions couple with hydrogen ions to form water, with a neutral pH, any material that releases them in solution will lower the concentration of hydrogen ions and raise the pH.