Unpatented = Unmentioned
For chemical Calvinist orthodoxy finds the notion that people should have a right to choose pharmacologically {sic} who and what they want to be profoundly offensive.--anonymous
Introduction
5-HTP, 5-hydroxytryptophan, is extracted from an African herb, Griffonia simplicifolia. It can be bought at health food and vitamin providers at brick or virtual stores. It often comes in small bottles of 30 capsules of 50 mg of the chemical, and is touted as a help to boost serotonin levels.
Effectiveness
Originally L-tryptophan, or L-5-HTP was used to treat depression, but it was made by a fermentation process that sometimes allowed contaminants into the product. Also 5-HTP is chemically closer to serotonin and thus more effective. There was from L-5-HTP possible allergic reaction called eosinophilia myalgia syndrome (EMS), whereby the overproduction of a substance in the blood stream that normally attacks microbial invaders causes symptoms including swelling, pain and rashes. The 5-HTP, however, is free from such maladies.
Depression
This alleviation of serotonin disorders, that have doctors prescribing selective serotonin re-uptake inhibitors (SSRI) such as Prozac (fluoxetine) or Zoloft (Sertaline), is fifty percent superior as proven in double blinded tests for twenty-five years. The added benefits include none of the side effects of the pharmaceuticals, dry mouth, sexual dysfunction, and the cost (unless you are talking money-bennies to those drug companies which cannot patent this herbal marvel.} Of course, 5-HTP is safer for those who have used up all of their dopamine and serotonin and need a smoothing out, when a reverse reaction to the 'wonderful fullness of life' on Ecstasy (MDMA: methylenedioxymethamphetamine) one of the intense re-uptake mechanism or any other strong mood enhancer or transformer.
Fibromyalgia
Studies by pain specialists have demonstrated 5-HTP's effectiveness at relieving the headaches, tiredness, and generalized pain at varying places on the body. This treatment helps because fibromyalgia is a "low serotonin" disorder.
Migraine
Ironically, 30 years ago researchers developed a drug, fenclonine, that blocks the tryptophan converting enzyme, because they thought preventing serotonin was the cure for migraines, but proved instead to worsen them - only in migraine sufferers, not normal subjects -- but now a breakthrough was made! At this time the EMS symptoms were discovered if one was given faulty produced tryptophans, and now, naturally, the superiority of 5-HTP.
Insomnia
They have shown in more than a hundred tests that high doses of 5-HTP cause no toxicity, and it is better than taking only melatonin, a naturally produced hormone that helps in our sleep patterns. Older people make less melatonin, and proper sleep is essential to healing. 5-HTP helps produce serotonin as well as melatonin that promote a feeling of well-being and relaxation. It is important to obtain the di-hydro form of 5-HTP in larger percentages (up to 100 mg) needed for the drowsiness inset, because normal 5-HTP in quantity can cause some stomach distress.
Panic Disorder
Researcher R.S. Kahn noticed subjects taking 5-HTP relieved of the associated high nervousness when "upset" in certain situations in their panic disorders.
Over-weightiness
Obese patients of Kahn treated with 5-HTP were able to feel satiated earlier, and thus reduce carbohydrate consumption.
Conclusion
One might try this product as an alternative to the costly ones that the large companies are putting out, but a bottle of 5-HTP is not covered by insurance, and costs around twenty U.S. dollars for 50 capsules of 50 mg. This writer, who tried it, felt as if his insides were swelling out like a human balloon full of some kind of welling energy. (Reminds me of my bad experience with Yohimbe), but later you sleep relatively peacefully. Maybe it is not a good thing for ones who are not depressed, as my experiment with Zoloft (Sertaline) was worse: anxious and headachey -- one's attitude becomes: apathy with a hard edge. 5-HTP does help one sleep, I concur, and perhaps the warnings of drowsiness should be heeded. As for using this herb to help or hinder other illegal drugs like MDMA, I do not recommend artificially messing with serotonin and dopamine inhibitors or enhancers-- as permanent damage can occur. Mixing this with SSRIs might cause problems including serotonin syndrome.
Source:
Dr. Murray Online
Baar.com
bltc.com